About

Reading a variant across registries means opening ClinVar, then gnomAD, then a literature search, and reconciling three different identifiers for the same thing by hand. VarInsight does the resolving and the fetching, and then gets out of the way.

The constraints it is built under

Every assertion carries a link to the record it came from. Nothing is summarised, re-worded or scored. There is no account, no database, and no analytics. There is no language model anywhere in it — the tool has no opinion to offer and no mechanism for forming one.

Those are not incidental. A tool that displays other people's assertions, with attribution, and generates none of its own is a different kind of thing from one that interprets — in how much you should trust it, and in what it is permitted to be.

Plain English, without paraphrasing

Because nothing is re-worded, a result is written in the registries' own terms —LOEUF, missense_variant, criteria provided, multiple submitters, no conflicts. Every one of them is underlined and carries a plain-English definition, in place or on hover, linked to the published definition it restates. See the glossary. A definition explains a word; it is never a statement about the variant on screen, which would be the interpretation this tool exists not to make.

How it works

A static site with one script. What you type is parsed into a canonical form, then three registries are queried in parallel directly from your browser. They are independent: if Europe PMC is down you still get the variant, and if MyVariant.info is down you still get the literature. Each section says which registry it came from and whether that registry had nothing, which is a different thing from an error.

The genome build

Shown on every result, because the same variant sits at different coordinates on GRCh37 and GRCh38 and both are real positions. The build is requested explicitly on every call and then checked against the record that comes back; a record in the wrong build is refused rather than displayed.

What it will not become

No batch upload, no VCF parsing, no API, no accounts, no summarisation. Those are all reasonable products; they are not this one.